These papers include correspondence, legal documents, financial records, family material, maps and plats, pictures, printed materials, diaires, and journals of geological expeditions. Also included are undated materials.

The Franz Boas Personal and Professional Papers contain a diverse assemblage of professional correspondence, family letters, and diaries, with a valuable series of essays and lectures by Boas on both professional and political topics (democracy, race, etc.). (NOTE: This collection is not to be confused with the much larger Franz Boas Papers collection (Mss.B.B61), which contains the vast majority of Boas's professional correspondence and was referred to as the "Professional Papers" in earlier decades.) During the half century leading up to the Second World War, Franz Boas helped to define academic anthropology in the United States. Trained as a geographer at the University of Heidelberg, Boas worked initially on the Inuit of Baffin Island and subsequently on the cultures of the Indians of the Northwest Pacific Coast, becoming a leading figure in American anthropology by the first decade of the twentieth century. As Professor of Anthropology at Columbia University, Boas made significant theoretical contributions to ethnology, linguistics, and physical anthropology, helping to ingrain the four fields approach in his discipline and introducing the concept of cultural relativism into wide currency. He was, as well, a committed Socialist and an ardent opponent of both racism and fascism.

A physician, natural historian, and professor at the University of Pennsylvania, Benjamin Smith Barton (1766-1815) was one of the central figures in Philadelphia's early national scientific establishment. Having received his medical training in European universities, Barton was appointed Professor at the University of Pennsylvania in 1789, lecturing on botany, materia medica, natural history. A prolific author, he established his reputation as one of the nation's preeminent botanists through his botanical text book The Elements of Botany (1803), but his contribtions to zoology, ethnology, and medicine were equally noteworthy. Barton's monograph on the "fascinating faculty" of the rattlesnake and his efforts in historical linguistics (New Views of the Origin of the Tribes and Nations of America, 1798) were widely read, and his Philadelphia Medical and Physical Journal (1804-1809) was one of the nation's first medical journals and an important outlet for natural historical research. The Barton Papers offer a comprehensive view of the professional work of Benjamin Smith Barton from the time of his return to the United States in 1789 until his death. The collection is divided into five series: Correspondence, Subject Files, Bound Volumes, Graphic Materials, and Printing Plates. The collection includes a particularly valuable series of botanical, medical, and natural historical drawings collected by Barton for research, reference, and publication. Among the many artists represented are William Bartram, Frederick Pursh, Pierre Turpin, and Benjamin Henry Latrobe.